منابع مشابه
Corticosteroids for alcoholic hepatitis--what's next?
Alcoholic hepatitis (AH) is observed in approximately 20% of heavy drinkers. The treatment of AH remains controversial and will, in the near future, constitute one of the main challenges to clinicians involved in the management of severe alcoholic liver disease [1]. Individual data from the last three randomized controlled trials (RCT), prospective studies and a recent RCT constantly showed tha...
متن کاملTreatment of severe alcoholic hepatitis with corticosteroids and pentoxifylline.
Despite being themost frequently abused drug for centuries, alcohol was not recognized as a direct hepatotoxin until the 1960s.1 Alcohol abuse accounts for the third leading preventable causeofdeath and the secondmost commoncauseof cirrhosis after hepatitis C virus infection in the United States.2,3 Alcoholichepatitis is a commoncomplicationofalcohol abuse; its severity can range frommild to se...
متن کاملAlcoholic hepatitis
Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and liver failure that generally occurs after decades of harmful alcohol consumption. Less severe forms of acute AH (AAH) frequently respond to alcoholic abstinence; whereas severe AAHs are characterized by a poor prognosis: up to 40-60% of these patients die within six months. Glucocorticoids currently remain the mainsta...
متن کاملThe Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids.
INTRODUCTION There is no consensus on the pharmacological treatment of alcoholic hepatitis. The Glasgow alcoholic hepatitis score (GAHS) has been shown to be more accurate than the modified Maddrey's discriminant function (mDF) in the prediction of outcome from alcoholic hepatitis. This study aimed to determine whether the GAHS was able to identify those patients who would benefit from corticos...
متن کاملLIVER DISEASE The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids
Introduction: There is no consensus on the pharmacological treatment of alcoholic hepatitis. The Glasgow alcoholic hepatitis score (GAHS) has been shown to be more accurate than the modified Maddrey’s discriminant function (mDF) in the prediction of outcome from alcoholic hepatitis. This study aimed to determine whether the GAHS was able to identify those patients who would benefit from cortico...
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ژورنال
عنوان ژورنال: Hepatology
سال: 1991
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.1840130132