Corticosteroids and alcoholic hepatitis

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Corticosteroids for alcoholic hepatitis--what's next?

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Alcoholic hepatitis

Alcoholic hepatitis (AH) is a clinical syndrome characterized by jaundice and liver failure that generally occurs after decades of harmful alcohol consumption. Less severe forms of acute AH (AAH) frequently respond to alcoholic abstinence; whereas severe AAHs are characterized by a poor prognosis: up to 40-60% of these patients die within six months. Glucocorticoids currently remain the mainsta...

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The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids.

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LIVER DISEASE The Glasgow alcoholic hepatitis score identifies patients who may benefit from corticosteroids

Introduction: There is no consensus on the pharmacological treatment of alcoholic hepatitis. The Glasgow alcoholic hepatitis score (GAHS) has been shown to be more accurate than the modified Maddrey’s discriminant function (mDF) in the prediction of outcome from alcoholic hepatitis. This study aimed to determine whether the GAHS was able to identify those patients who would benefit from cortico...

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ژورنال

عنوان ژورنال: Hepatology

سال: 1991

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.1840130132